Treatment with drugs is fundamental to modern therapy of psychiatric disorders. In order to effectively utilize drug treatment, physicians and psychiatrists must have a sound understanding of the pharmacology of the brain. A coherent explanation of the underlying principles of drug action and interaction from neuroscience to clinical applications is provided. It explains why certain drugs and various types of pharmaceuticals are used to treat specific disorders, how they work and to what effect. The appendices provide a glossary, index of proprietary names and suggestions for further reading.